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HYPERTENSION
IN PREGNANCY
-Methyldopa
is recommended for females with hypertension that is first diagnosed in
pregnancy.
-Hydralazine
is the IV drug recommended for severe hypertension during pregnancy.
It is also used for the treatment of eclampsia and pre-eclampsia.
-Diuretics
are indicated for the treatment of chronic hypertension if they are
prescribed before the start of conception.
Diuretics are also indicated in salt-sensitive pregnant females.
-Beta-blockers
such as atenolol, metoprolol, and labetalol have been shown to be safe in
late pregnancy, but may cause fetal growth retardation when used in early
pregnancy.
-Calcium
blockers may produce hypotension if given with magnesium to treat pre-eclampsia
and/or eclampsia
-ACE
inhibitors, and Angiotensin II receptor blockers are contraindicated in
pregnancy since they have been associated with fetal death and renal failure
during the last two trimesters of pregnancy.
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