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PHEOCHROMOCYTOMA AND HYPERTENSION
-IV phentolamine (alpha 1 and alpha 2
receptor blocker) is indicated
to treat severe HTN secondary to pheochromocytoma.
Beta-blockers should only be used after phentolamine has
blocked the alpha receptors. If
the beta-blocker is given prior to starting phentolamine,
the beta-blocker may worsen the hypertension and/or cause coronary
ischemia due to catecholamines acting on the
alpha receptors that are unblocked.
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